VO vs XBI
Vanguard Mid-Cap ETF vs SPDR S&P Biotech ETF
VO$82.60
Vanguard Mid-Cap ETF
US mid-cap stocks across sectors.
Expense: 0.03%Yield: 1.35%
XBI$156.41
SPDR S&P Biotech ETF
Equal-weight biotech stocks in the S&P Biotech Index.
Expense: 0.35%Yield: 0.35%
Quick take
- • VO has the lower expense ratio at 0.03% vs 0.35% for XBI.
- • VO pays a higher dividend yield (1.35%).
Side-by-side metrics
| Metric | VO | XBI |
|---|---|---|
Expense ratio Annual fee. Lower is better. | 0.03% | 0.35% |
Dividend yield Trailing 12-month yield. | 1.35% | 0.35% |
AUM Assets under management — bigger funds are typically more liquid. | $222.43B | $10.92B |
YTD return | 13.60% | 28.80% |
1-year return | — | — |
3-year return Annualized. | — | — |
5-year return Annualized. | — | — |
10-year return Annualized. | — | — |
Beta (3Y) Volatility relative to the market. Closer to 1 = market-like. | 0.91 | 1.01 |
P/E ratio | 22.16 | — |
Last price | $82.60 | $156.41 |
Inception | — | — |
Issuer | Vanguard | State Street |
VO top holdings
Top holdings · VO
| NET | Cloudflare Inc | 1.11% |
| VLO | Valero Energy Corp | 1.10% |
| MPC | Marathon Petroleum Corp | 1.10% |
| PSX | Phillips 66 | 1.01% |
| PWR | Quanta Services Inc | 0.95% |
| VRT | Vertiv Holdings Co Class A | 0.92% |
| DDOG | Datadog Inc Class A | 0.91% |
| HWM | Howmet Aerospace Inc | 0.89% |
| HOOD | Robinhood Markets Inc Class A | 0.88% |
| LITE | Lumentum Holdings Inc | 0.86% |
Sector breakdown · VO
Real Estate4.8%
Consumer Cyclical8.7%
Basic Materials4.1%
Consumer Defensive4.8%
Technology17.6%
Communication Services2.1%
Financial Services13.8%
Utilities7.7%
Industrials18.5%
Energy8.6%
Healthcare9.3%
XBI top holdings
Top holdings · XBI
| MRNA | Moderna Inc | 2.37% |
| NTRA | Natera Inc | 1.82% |
| HALO | Halozyme Therapeutics Inc | 1.77% |
| TWST | Twist Bioscience Corp | 1.77% |
| BIIB | Biogen Inc | 1.75% |
| AMGN | Amgen Inc | 1.73% |
| EXEL | Exelixis Inc | 1.73% |
| UTHR | United Therapeutics Corp | 1.72% |
| ABBV | AbbVie Inc | 1.71% |
| GILD | Gilead Sciences Inc | 1.70% |
Sector breakdown · XBI
Financial Services0.6%
Healthcare99.3%
About VO
VO (Vanguard Mid-Cap ETF) is US mid-cap stocks across sectors. Managed by Vanguard, the fund carries $222.4B in assets under management, an expense ratio of 0.03%, a dividend yield of 1.35%. Its largest holding is Cloudflare Inc (NET), which represents 1.1% of the portfolio. Real Estate is the fund's largest sector exposure at 4.8%.
About XBI
XBI (SPDR S&P Biotech ETF) is Equal-weight biotech stocks in the S&P Biotech Index. Managed by State Street, the fund carries $10.9B in assets under management, an expense ratio of 0.35%, a dividend yield of 0.35%. Its largest holding is Moderna Inc (MRNA), which represents 2.4% of the portfolio. Financial Services is the fund's largest sector exposure at 0.6%.