VOO vs XBI

Vanguard S&P 500 ETF vs SPDR S&P Biotech ETF

Quick take
  • VOO has the lower expense ratio at 0.03% vs 0.35% for XBI.
  • VOO pays a higher dividend yield (1.08%).

Side-by-side metrics

MetricVOOXBI
Expense ratio
Annual fee. Lower is better.
0.03%0.35%
Dividend yield
Trailing 12-month yield.
1.08%0.34%
AUM
Assets under management — bigger funds are typically more liquid.
$1.60T$8.30B
YTD return
7.92%12.92%
1-year return
3-year return
Annualized.
5-year return
Annualized.
10-year return
Annualized.
Beta (3Y)
Volatility relative to the market. Closer to 1 = market-like.
1.001.09
P/E ratio
29.04
Last price
$672.54$133.66
Inception
Issuer
VanguardState Street

VOO top holdings

Top holdings · VOO
NVDANVIDIA Corp7.58%
AAPLApple Inc6.67%
MSFTMicrosoft Corp4.92%
AMZNAmazon.com Inc3.64%
GOOGLAlphabet Inc Class A3.00%
AVGOBroadcom Inc2.63%
GOOGAlphabet Inc Class C2.40%
METAMeta Platforms Inc Class A2.24%
TSLATesla Inc1.87%
BRK-BBerkshire Hathaway Inc Class B1.57%
Sector breakdown · VOO
Real Estate1.9%
Consumer Cyclical10.0%
Basic Materials1.9%
Consumer Defensive5.3%
Technology33.6%
Communication Services10.5%
Financial Services12.2%
Utilities2.5%
Industrials8.5%
Energy4.0%
Healthcare9.5%

XBI top holdings

Top holdings · XBI
APLSApellis Pharmaceuticals Inc1.87%
RVMDRevolution Medicines Inc Ordinary Shares1.65%
TVTXTravere Therapeutics Inc Ordinary Shares1.62%
ARWRArrowhead Pharmaceuticals Inc1.44%
TWSTTwist Bioscience Corp1.42%
SMMTSummit Therapeutics Inc Ordinary Shares1.40%
ALKSAlkermes PLC1.38%
TGTXTG Therapeutics Inc1.37%
MDGLMadrigal Pharmaceuticals Inc1.36%
BEAMBeam Therapeutics Inc1.32%
Sector breakdown · XBI
Financial Services0.2%
Healthcare99.8%

About VOO

VOO (Vanguard S&P 500 ETF) is Tracks the S&P 500 index of 500 large US companies. Managed by Vanguard, the fund carries $1.6T in assets under management, an expense ratio of 0.03%, a dividend yield of 1.08%. Its largest holding is NVIDIA Corp (NVDA), which represents 7.6% of the portfolio. Real Estate is the fund's largest sector exposure at 1.9%.

About XBI

XBI (SPDR S&P Biotech ETF) is Equal-weight biotech stocks in the S&P Biotech Index. Managed by State Street, the fund carries $8.3B in assets under management, an expense ratio of 0.35%, a dividend yield of 0.34%. Its largest holding is Apellis Pharmaceuticals Inc (APLS), which represents 1.9% of the portfolio. Financial Services is the fund's largest sector exposure at 0.2%.