VOO vs XBI

Vanguard S&P 500 ETF vs SPDR S&P Biotech ETF

Quick take
  • VOO has the lower expense ratio at 0.03% vs 0.35% for XBI.
  • VOO pays a higher dividend yield (1.07%).

Side-by-side metrics

MetricVOOXBI
Expense ratio
Annual fee. Lower is better.
0.03%0.35%
Dividend yield
Trailing 12-month yield.
1.07%0.36%
AUM
Assets under management — bigger funds are typically more liquid.
$1.67T$10.73B
YTD return
9.94%33.79%
1-year return
3-year return
Annualized.
5-year return
Annualized.
10-year return
Annualized.
Beta (3Y)
Volatility relative to the market. Closer to 1 = market-like.
1.001.10
P/E ratio
26.96
Last price
$690.84$164.01
Inception
Issuer
VanguardState Street

VOO top holdings

Top holdings · VOO
NVDANVIDIA Corp7.89%
AAPLApple Inc7.04%
MSFTMicrosoft Corp5.14%
AMZNAmazon.com Inc4.06%
GOOGLAlphabet Inc Class A3.40%
AVGOBroadcom Inc3.26%
GOOGAlphabet Inc Class C2.71%
METAMeta Platforms Inc Class A2.13%
TSLATesla Inc1.88%
MUMicron Technology Inc1.68%
Sector breakdown · VOO
Real Estate1.8%
Consumer Cyclical9.9%
Basic Materials1.7%
Consumer Defensive4.5%
Technology39.1%
Communication Services10.7%
Financial Services10.9%
Utilities2.1%
Industrials7.8%
Energy3.1%
Healthcare8.3%

XBI top holdings

Top holdings · XBI
APGEApogee Therapeutics Inc1.49%
MRNAModerna Inc1.41%
TWSTTwist Bioscience Corp1.41%
ORKAOruka Therapeutics Inc1.38%
KYMRKymera Therapeutics Inc Ordinary Shares1.36%
VKTXViking Therapeutics Inc1.30%
PRAXPraxis Precision Medicines Inc Ordinary Shares1.29%
ERASErasca Inc1.27%
RVMDRevolution Medicines Inc Ordinary Shares1.20%
RYTMRhythm Pharmaceuticals Inc1.20%
Sector breakdown · XBI
Financial Services0.5%
Healthcare99.5%

About VOO

VOO (Vanguard S&P 500 ETF) is Tracks the S&P 500 index of 500 large US companies. Managed by Vanguard, the fund carries $1.7T in assets under management, an expense ratio of 0.03%, a dividend yield of 1.07%. Its largest holding is NVIDIA Corp (NVDA), which represents 7.9% of the portfolio. Real Estate is the fund's largest sector exposure at 1.8%.

About XBI

XBI (SPDR S&P Biotech ETF) is Equal-weight biotech stocks in the S&P Biotech Index. Managed by State Street, the fund carries $10.7B in assets under management, an expense ratio of 0.35%, a dividend yield of 0.36%. Its largest holding is Apogee Therapeutics Inc (APGE), which represents 1.5% of the portfolio. Financial Services is the fund's largest sector exposure at 0.5%.