VOO vs XBI

Vanguard S&P 500 ETF vs SPDR S&P Biotech ETF

Quick take
  • • VOO has the lower expense ratio at 0.03% vs 0.35% for XBI.
  • • VOO pays a higher dividend yield (1.07%).

Side-by-side metrics

MetricVOOXBI
Expense ratio
Annual fee. Lower is better.
0.03%0.35%
Dividend yield
Trailing 12-month yield.
1.07%0.35%
AUM
Assets under management — bigger funds are typically more liquid.
$1.74T$10.92B
YTD return
11.29%28.80%
1-year return
——
3-year return
Annualized.
——
5-year return
Annualized.
——
10-year return
Annualized.
——
Beta (3Y)
Volatility relative to the market. Closer to 1 = market-like.
0.971.01
P/E ratio
24.17—
Last price
$699.75$156.41
Inception
——
Issuer
VanguardState Street

VOO top holdings

Top holdings · VOO
NVDANVIDIA Corp8.39%
AAPLApple Inc7.38%
MSFTMicrosoft Corp5.78%
AMZNAmazon.com Inc3.71%
GOOGLAlphabet Inc Class A3.07%
AVGOBroadcom Inc2.54%
GOOGAlphabet Inc Class C2.45%
METAMeta Platforms Inc Class A2.43%
MUMicron Technology Inc1.83%
TSLATesla Inc1.52%
Sector breakdown · VOO
Real Estate1.7%
Consumer Cyclical8.8%
Basic Materials1.6%
Consumer Defensive4.3%
Technology40.5%
Communication Services9.9%
Financial Services11.1%
Utilities1.9%
Industrials7.6%
Energy3.4%
Healthcare9.3%

XBI top holdings

Top holdings · XBI
MRNAModerna Inc2.37%
NTRANatera Inc1.82%
HALOHalozyme Therapeutics Inc1.77%
TWSTTwist Bioscience Corp1.77%
BIIBBiogen Inc1.75%
AMGNAmgen Inc1.73%
EXELExelixis Inc1.73%
UTHRUnited Therapeutics Corp1.72%
ABBVAbbVie Inc1.71%
GILDGilead Sciences Inc1.70%
Sector breakdown · XBI
Financial Services0.6%
Healthcare99.3%

About VOO

VOO (Vanguard S&P 500 ETF) is Tracks the S&P 500 index of 500 large US companies. Managed by Vanguard, the fund carries $1.7T in assets under management, an expense ratio of 0.03%, a dividend yield of 1.07%. Its largest holding is NVIDIA Corp (NVDA), which represents 8.4% of the portfolio. Real Estate is the fund's largest sector exposure at 1.7%.

About XBI

XBI (SPDR S&P Biotech ETF) is Equal-weight biotech stocks in the S&P Biotech Index. Managed by State Street, the fund carries $10.9B in assets under management, an expense ratio of 0.35%, a dividend yield of 0.35%. Its largest holding is Moderna Inc (MRNA), which represents 2.4% of the portfolio. Financial Services is the fund's largest sector exposure at 0.6%.